This paper discusses some of the key practical MU-MIMO drawbacks in the baseband design, their development through the LTE evolution from Release 8 to Release 12, and potential ways to address those shortcomings. System aspects such as accurate feedback link, importance of MU-MIMO channel models, and antenna configuration, as well as receiver design aspects such as channel estimation and detection procedures, are discussed in this article and evaluated in various MU-MIMO practical scenarios.