Released in 2011, the ISO26262 standard is the major global regulation governing functional safety in road vehicles. Functional safety-related design activities at ams have led to a large portfolio of advanced diagnosis IP such as Continuous integrity checks for on-chip-memory, Self-test of the signal processing blocks, and Read-back of the status of device-drivers and outputs. With the adoption of the ISO standard, major concerns about an increase of the development cost and device die size were raised in the semiconductor industry. Today, the standard is regarded as a critical aid to approach the design-in of safety requirements in a more analytical, disciplined manner.