Prior to the fabrication, assembly, and power on of a board, a thorough review of the board layout is essential to meet the demands of time to market. In this document we will outline the best practices to guide the user through the process of doing an effective layout review. Aimed at the system engineer, this document will explain the process of how the layout review works in the lab, and the required documents and reference materials for the review. This process includes inspecting the board, reviewing the power delivery, reviewing clocks, and reviewing the individual interfaces.