Over 82 million people in the developed world face challenges each day when attempting to read a variety of printed materials. The Intel Reader is the output of years of research into end-users who experience difficulty reading text for a variety of reasons. This article reviews the diverse end-user population for this technology, and we identify unique sub-population requirements that were distilled into a set of common parameters. It explores many of the design challenges, tradeoffs, and unexpected discoveries that led to the final definition for the Intel Reader.